Which diagnostic measure is most accurate in detecting neural tube defects?

Which diagnostic measure is most accurate in detecting neural tube defects?


a) Presence of high maternal levels of albumin after 12th week of gestation
b) Significant level of alpha-fetoprotein present in amniotic fluid
c) Amniocentesis for lecithin-sphingomyelin (L/S) ratio
d) Flat plate of the lower abdomen after the 23rd week of gestation


Answer: b)Significant level of alpha-fetoprotein present in amniotic fluid


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